Key result
Excision and postoperative radiation therapy for myxoinflammatory fibroblastic sarcoma resulted in no recurrence or metastasis at 12 years postoperatively.
Case Report (n=1)
Excision and postoperative radiation therapy resulted in 12-year disease-free survival in a rare case of myxoinflammatory fibroblastic sarcoma.
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May support excision plus radiation for this rare sarcoma; hypothesis-generating and should not yet change practice.
Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare, painless, and intermediate (rarely metastasizing) fibroblastic tumor, which commonly occurs in the extremities, with an equal sex predilection. This sarcoma is composed of a mixed inflammatory infiltrate along with spindled, epithelioid, and bizarre tumor cells in a background of hyaline and myxoid areas. In spite of such a distinctive morphology, the tumor can be a diagnostic challenge, simulating inflammatory conditions as well as neoplastic nature. For accurate diagnosis, the tumor requires extensive clinical, radiological, and pathological investigations. We present a case of MIFS in a 19-year-old female who presented with a mass in the left ankle. After appropriate excision and postoperative radiation therapy, she is free of disease, including recurrence and metastasis, at 12 years postoperatively.
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Kato et al. (2015) conducted a case report in Myxoinflammatory fibroblastic sarcoma (n=1). Excision and postoperative radiation therapy was evaluated on Disease recurrence and metastasis. Excision and postoperative radiation therapy for myxoinflammatory fibroblastic sarcoma resulted in no recurrence or metastasis at 12 years postoperatively.
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