Transcatheter Device Closure of Ventricular Septal Defect in Children: A Retrospective Study at Pediatric Cardiac Center, Children’s Hospital, Ain Shams University

Background: Twenty percent of all isolated congenital cardiac abnormalities in children are due to ventricular septal defect (VSD). Congestive heart failure, failure to thrive, enlargement of the left atrium and left ventricle, or high pulmonary artery pressures are common indications for transcatheter closure of a moderately sized VSD (or both). Objective: This study aimed to study the safety, efficacy, and outcome of transcatheter closure of VSDs in Paediatric Cardiac Catheter Unit in children's Hospital, Ain Shams University. Subjects and Methods: This retrospective cohort study took place at Children's Hospital, Ain Shams University from January 2018 to January 2021 on 35 children with VSD. All VSD patients who underwent diagnostic or interventional cardiac catheterization in the last 3 years were recruited. Medical history, physical exam, pre-intervention investigation, or procedural data were collected from patient records. Results: In 17 patients (48.6%), ADO II was employed, followed by muscle amplatzer VSD, PDA, and ADO I. (5.7 %). One patient (2.9%) experienced hemolysis and blood transfusion. The percentage of ADOI devices in complicated patients was statistically higher than in non-complicated patients (p = 0.001), but there was no difference in PDA, ADOII, or muscle amplatzer devices. Conclusion: Transcatheter closure of congenital VSDs is successful. Transcatheter closure is a feasible and practical treatment for different VSD shapes.