Key result
Persimmon extract administered at 100 mg/kg significantly reduced liver lipid accumulation (76.8 vs 98.8 mg/g) and liver damage in mice fed a high-fat diet.
Absolute Event Rate: 76.8% vs 98.8%
p-value: p=<0.05
Persimmon extract mitigated HFD-induced steatosis and lipotoxicity in mice; leaves open translation to human metabolic liver disease.
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Kang et al. (2022) studied High-fat diet-induced lipid accumulation and liver damage (n=28). Persimmon extract (DKE) vs. High-fat diet (HFD) alone was evaluated on Liver lipid accumulation (mg/g) (p=<0.05). Persimmon extract administered at 100 mg/kg significantly reduced liver lipid accumulation (76.8 vs 98.8 mg/g) and liver damage in mice fed a high-fat diet.
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