Key result
Higher 24-hour ambulatory SBP is linked to ~22% increased risk of new-onset AF per 10 mm Hg.
Why the study?
The influence of clinic and ambulatory blood pressure on the risk of new-onset atrial fibrillation in treated hypertensive patients was unclear.
Does ambulatory blood pressure better predict new-onset atrial fibrillation compared to clinic blood pressure in treated hypertensive patients?
Population
2135 sequential treated hypertensive patients aged >40 years
Comparison
Ambulatory systolic BP (daytime, nighttime, 24-h) vs clinic systolic BP
Design
Cohort study
Follow-up
Mean 9.7 years (range 0.4-20 years)
Authors
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Supports ambulatory BP monitoring for AF risk stratification in treated hypertension; leaves open whether targeting 24-h BP prevents new-onset AF.
Cohort (n=2,135)
Does ambulatory blood pressure better predict new-onset atrial fibrillation compared to clinic blood pressure in treated hypertensive patients?
Hazard Ratio: 1.22 (95% CI 1.06–1.4)
Ambulatory blood pressure parameters (daytime, nighttime, and 24-h systolic BP) are superior to clinic systolic BP in predicting the risk of new-onset atrial fibrillation in treated hypertensive patients.
Coccina et al. (2020) conducted a cohort in Hypertension (n=2,135). Ambulatory systolic blood pressure vs. Clinic systolic blood pressure was evaluated on New-onset atrial fibrillation (HR 1.22, 95% CI 1.06-1.40). Higher 24-hour ambulatory systolic blood pressure was significantly associated with an increased risk of new-onset atrial fibrillation (HR 1.22; 95% CI 1.06-1.40 per 10 mm Hg increment).
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