Key result
Pre-eclampsia is linked to ~3.5-fold higher urinary albumin excretion at 3-5 years postpartum.
Why the study?
Detection of microalbuminuria after pregnancy complicated by pre-eclampsia may have predictive value for later development of chronic hypertension or renal disease.
Does a history of pregnancy complicated by pre-eclampsia increase the occurrence of microalbuminuria compared to normal pregnancy?
Population
48 women with pregnancy complicated by pre-eclampsia and 44 women after normal pregnancy
Comparison
Pregnancy complicated by pre-eclampsia vs normal pregnancy
Design
Cohort study
Follow-up
3-5 years
Authors
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May flag future hypertension risk after pre-eclampsia; leaves open whether screening improves outcomes in this population.
Cohort (n=92)
Does a history of pregnancy complicated by pre-eclampsia increase the occurrence of microalbuminuria compared to normal pregnancy?
Absolute Event Rate: 23.5% vs 6.7%
p-value: p=0.001
A history of pre-eclampsia is associated with significantly higher urinary albumin excretion rates up to 3-5 years post-pregnancy, indicating a potential marker for underlying vascular disease.
Jacob Bar (1999) conducted a cohort in Pregnancy complicated by pre-eclampsia (n=92). Pregnancy complicated by pre-eclampsia vs. Normal pregnancy was evaluated on Mean urinary albumin excretion rate at 3-5 years after delivery (p=0.001). Pregnancy complicated by pre-eclampsia was associated with a higher mean urinary albumin excretion rate at 3-5 years postpartum compared to normal pregnancy (23.5 vs 6.7 mg/24 h; P=0.001).
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