Key result
Neonatal severe thrombosis therapies lack robust evidence to guide optimal treatment strategies.
Why the study?
Severe thromboses in neonates present diagnostic and therapeutic challenges with limited data on ideal treatment strategies for specific thrombosis types.
This review discusses the management and potential therapies for severe thromboses in neonates, highlighting the current lack of data for ideal therapies.
Management of severe neonatal thromboses demands individualized decisions with subspecialty support; leaves open the need for prospective trials to define optimal therapies.
Severe thrombosis in the neonate presents a diagnostic challenge to the clinician as the benefits and risks for treatment must be weighed with every medical decision. Aortic thromboses, large right atrial thromboses, and septic thrombophlebitis present unique clinical challenges that must be managed in the appropriate clinical setting with appropriate subspecialty support. Unfortunately, there is limited data on what the ideal therapy should be for these specific types of cases. In this review, we will discuss these types of severe thromboses that may occur in neonates and potential therapies that may offer benefits.
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Saxonhouse et al. (2022) conducted a review in Severe thromboses. Therapies for severe thromboses was evaluated. Potential therapies for severe thromboses in neonates, including aortic and right atrial thromboses, are discussed in this review, highlighting the limited data on ideal treatment strategies.
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