Key result
Pharmacist-managed telephone lipid clinic linked to ~44 mg/dL reduction in LDL-C.
Why the study?
Pharmacist-managed lipid clinics effectively lower LDL-C in veterans, and telephone management offers a convenient alternative, but its impact on lipid levels needed evaluation.
Does a pharmacist-managed telephone lipid clinic improve LDL-C levels and goal attainment in veterans?
Observational
No
Does a pharmacist-managed telephone lipid clinic improve LDL-C levels and goal attainment in veterans?
Mean Difference: 44.3
p-value: p=< 0.001
A pharmacist-managed telephone lipid clinic significantly reduces LDL-C levels and improves goal attainment in a veteran population.
May support pharmacist-managed tele-lipid clinics; leaves open need for randomized outcome trials before practice change.
BACKGROUND: Heart disease is one of the leading causes of death and disability in the US, with dyslipidemia being a significant risk factor. Pharmacist-managed lipid clinics have been shown to be effective in lowering low-density lipoprotein cholesterol (LDL-C) values in the veteran population. In addition, telephone-managed clinics are known to be an effective method to manage anticoagulation therapy. This type of appointment is very convenient; it reduces travel and waiting times, costs, and potential no-show rates. OBJECTIVE: To assess changes in LDL-C levels from baseline to follow-up and number of patients attaining LDL-C goals during enrollment in the pharmacist-managed telephone lipid clinic (PMTLC). METHODS: A retrospective chart review was conducted on all patients enrolled in the clinic who had follow-up laboratory data available. Baseline LDL-C values were compared with values obtained at follow-up. Patients' total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) values were also collected and analyzed for improvement. The agents used, number of antidyslipidemic medications, and the incidence of adverse drug reactions prior to and during clinic enrollment were also collected. RESULTS: Patients in the PMTLC had a mean +/- SD reduction in LDL-C of 44.3 +/- 45.2 mg/dL (p < 0.001). In addition, 10 (28%) patients achieved the LDL-C goal (p = 0.002). Mean reductions in TC and TG levels were 44 mg/dL (18%) and 14.6 mg/dL (8%), respectively. There was no significant change in HDL-C levels. CONCLUSIONS: The PMTLC at the Erie, PA, Veterans Affairs Medical Center demonstrated statistically significant reduction in patients' LDL-C levels and increase in the number of patients attaining LDL-C goal.
No takes yet. Share an insight, caveat, or question.
Fabbio et al. (2009) conducted an observational in Dyslipidemia. Pharmacist-managed telephone lipid clinic (PMTLC) vs. Baseline (pre-enrollment) was evaluated on Changes in LDL-C levels from baseline to follow-up (mean reduction 44.3 mg/dL, p=< 0.001). A pharmacist-managed telephone lipid clinic significantly reduced LDL-C levels by a mean of 44.3 mg/dL (p < 0.001) and increased the number of patients attaining their LDL-C goal.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: