Key result
Elevated renal resistive index ≥0.70 is linked to ~28% lower eGFR in hypertensive patients.
Why the study?
Hypertension is a leading cause of kidney dysfunction, and renal resistive index (RRI) may help detect early kidney dysfunction in hypertensive patients.
Does renal resistive index (RRI) evaluation with intrarenal doppler ultrasound detect early kidney dysfunction in hypertensive patients?
Cross-Sectional (n=61)
No
Does renal resistive index (RRI) evaluation with intrarenal doppler ultrasound detect early kidney dysfunction in hypertensive patients?
Absolute Event Rate: 64.91% vs 90.29%
p-value: p=0.030
An elevated renal resistive index (≥ 0.70) is significantly associated with lower eGFR in hypertensive patients, suggesting its utility as a marker for early renal dysfunction.
Renal resistive index measurement should not yet change hypertension practice; leaves open its value as a renal function marker pending prospective studies.
Background: Hypertension (HTN) is a leading cause of kidney dysfunction. Renal resistive index (RRI) was an index to evaluate arterial compliance and/or resistance, reflecting the reduction of kidney function and microalbuminuria. We investigated the relationship of RRI in hypertensive patients to detect kidney dysfunction early detection. Material and methods: This was a cross-sectional study at Wahidin Sudirohusodo hospital in June–November 2022. All hypertensive patients were evaluated for RRI. RRI was examined with intrarenal doppler ultrasound, and a cutoff ≥ 0.70 were used. Results: This study included 61 subjects. Thirty-five subjects were female, and 26 subjects were male 90.2% of subjects were below 60 years. Estimated glomerular filtration rate (eGFR) level was 90.29 ± 25.19 in RRI < 0.7 and 64.91 ± 31.79 in RRI ≥ 0.7. Our study found there was a significant difference between anti-hypertensive treatment and eGFR level with the RRI group (p-value < 0.05). There was no significant difference in sex, age, proteinuria, and HTN control status in both RRI groups. Conclusion: The renal resistive index is a useful marker for early renal dysfunction in hypertensive patients despite normal eGFR.
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Kasim et al. (2023) conducted a cross-sectional in Hypertension (n=61). Renal resistive index ≥ 0.70 vs. Renal resistive index < 0.70 was evaluated on Estimated glomerular filtration rate (eGFR) (p=0.030). An elevated renal resistive index (≥ 0.70) in hypertensive patients was significantly associated with a lower estimated glomerular filtration rate compared to those with an index < 0.70 (64.91 vs 90.29, p=0.030).
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