Key result
Perioperative statin therapy shows promise as an adjunctive strategy to prevent postoperative atrial fibrillation.
Why the study?
There is a strong need for non-antiarrhythmic, adjunctive therapies to prevent postoperative atrial fibrillation due to limitations of current antiarrhythmic agents.
Does perioperative statin therapy prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Population
Patients undergoing cardiac surgery
Comparison
Perioperative statin therapy vs no statin therapy
Design
Review
Authors
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Highlights unmet need for adjunctive POAF prevention; leaves open which non-antiarrhythmic strategies warrant prospective testing.
Does perioperative statin therapy prevent postoperative atrial fibrillation in patients undergoing cardiac surgery?
Perioperative statin therapy may serve as an adjunctive strategy to prevent postoperative atrial fibrillation through pleiotropic effects independent of LDL lowering.
Blanchard et al. (2007) conducted a review in postoperative atrial fibrillation. Statins was evaluated. Perioperative statin therapy may represent an important non-antiarrhythmic, adjunctive therapeutic strategy for the prevention of postoperative atrial fibrillation.
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