Why the study?
Acute myocardial infarction with significant atherosclerosis is rarely reported in patients with apical hypertrophic cardiomyopathy, and no prior reports exist of apical HCM combined with acute myocardial infarction and multiple coronary thrombosis.
Case Report (n=1)
No
This case highlights the rare occurrence of acute myocardial infarction with multiple coronary thrombosis in a patient with apical hypertrophic cardiomyopathy.
Apical HCM does not exclude multivessel CAD; this first case leaves open true incidence and clinical implications.
Introduction Apical hypertrophic cardiomyopathy is a variant of hypertrophic cardiomyopathy (HCM) characterized by a spade-shape configuration on echocardiographic examination. It often accompanies a quite normal or even larger coronary arteriogram. Therefore acute myocardial infarction with significant atherosclerosis is rarely reported in patients with apical HCM or hypertrophic cardiomyopathy. Also there was no report of apical HCM combined with acute myocardial infarction and multiple coronary thrombosis. We report a rare case of typical apical HCM, who developed acute myocardial infarction due to multiple coronary thrombosis.
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Jung et al. (2008) conducted a case report in Apical hypertrophic cardiomyopathy with acute myocardial infarction (n=1). Percutaneous coronary intervention and medical therapy (abciximab, heparin, urokinase) was evaluated.
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