Key result
Clinic and ambulatory SBP reductions equally predict left ventricular mass regression in hypertension.
Why the study?
The extent to which changes in conventional and ambulatory blood pressure predict regression of left ventricular mass index in hypertensive black African patients was unclear.
Do changes in conventional and ambulatory blood pressure predict regression of left ventricular mass index in response to antihypertensive treatment in black African hypertensive patients?
Population
173 black African patients with sustained hypertension including 64 previously untreated and 109 previously treated
Comparison
Previously untreated vs previously treated patients with antihypertensive treatment to reduce daytime diastolic BP below 90 mm Hg
Design
Single-center cohort study
Follow-up
4 months
Authors
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Both clinic and ambulatory BP reductions may equally inform LV mass regression assessment; leaves open optimal monitoring choice in prospective trials.
Cohort (n=173)
No
Do changes in conventional and ambulatory blood pressure predict regression of left ventricular mass index in response to antihypertensive treatment in black African hypertensive patients?
Effect estimate: r = 0.34
p-value: p=0.005
Reductions in clinic and ambulatory systolic pressure equally predict the regression in left ventricular mass index in previously untreated black African patients with sustained hypertension.
Skudicky et al. (2002) conducted a cohort in sustained hypertension (n=173). Antihypertensive treatment vs. Previously treated patients was evaluated on Correlation between decrease in conventional systolic BP and regression in LVM index in previously untreated patients (r = 0.34, p=0.005). In previously untreated hypertensive patients, reductions in clinic and ambulatory systolic pressure in response to antihypertensive treatment equally predicted the regression in LVM index.
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