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January 1, 2011Journal of Korean Medical ScienceOpen Access

Prehypertension was an independent predictor for incident hypertension over 5 years, increasing the odds of developing hypertension by 2.25 times compared to normal blood pressure.

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Population

730 non-hypertensive individuals (265 males; mean age = 56.6 ± 11.1 years) from a rural area of Daegu, Korea.

Design

Cohort

Follow-up

5 years

Key result

Prehypertension was an independent predictor for incident hypertension over 5 years, increasing the odds of developing hypertension by 2.25 times compared to normal blood pressure.

Authors

JLJang Hoon LeeInterventional CardiologyDYDong Heon YangHeart Failure / CardiomyopathyHPHun Sik ParkKyungpook National University Hospital

Discussion

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Overview

May warrant closer surveillance in prehypertensive rural adults; leaves open optimal prevention strategies pending interventional trials.

Study Design

Type

Cohort (n=730)

Structured PICO

P
Population
730 non-hypertensive adults aged 20 years and older from a rural area of Korea, followed for 5 years to assess the incidence of hypertension.
O
Outcome
Incidence of hypertension (defined as either a new diagnosis of hypertension or self-reports of newly initiated antihypertensive treatment) over 5 years

Main Result

Odds Ratio: 2.25 (95% CI 1.48–3.42)

Absolute Event Rate: 32.7% vs 16.6%

p-value: p=<0.001

Over a 5-year period, more than a quarter of non-hypertensive Korean adults developed hypertension, highlighting prehypertension and older age as strong predictors that warrant preventive approaches.

Limitations

  • Blood pressure measurements were based on a single day, which may cause variation.
  • Loss to follow-up rate exceeded 20%, introducing potential selection bias.
  • Target population was confined to a rural area of Daegu City, limiting generalizability.

Cite This Study

Lee et al. (2011) conducted a cohort in Hypertension (n=730). Prehypertension vs. Normal blood pressure was evaluated on Incident hypertension (OR 2.25, 95% CI 1.48-3.42, p=<0.001). Prehypertension was an independent predictor for incident hypertension over 5 years, increasing the odds of developing hypertension by 2.25 times compared to normal blood pressure.

synapsesocial.com/papers/6ab367f24ddda921142bc8c7https://doi.org/10.3346/jkms.2011.26.10.1286
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Incidence and risk factors for progression from prehypertension to hypertension: a 12-year Korean Cohort Study2020 · 23 citations
  2. 2Prevalence of prehypertension and hypertension in a Korean population: Korean National Health and Nutrition Survey 20012006 · 174 citations
  3. 3Prevalence, Awareness, Treatment, and Control of Hypertension in Korea2019 · 78 citations
  4. 4Korea hypertension fact sheet 20182018 · 144 citations
  5. 5Prevalence, awareness, treatment, control and risk factors of hypertension in Korea: the Ansan study2001 · 161 citations