Key result
A 28-year-old female presented with small cell osteosarcoma of the mandible, characterized by sheets of small round cells and osteoid, distinguishing it from Ewing's sarcoma.
Case Report (n=1)
Highlights the diagnostic importance of identifying osteoid to distinguish small cell osteosarcoma from other small round cell tumors like Ewing's sarcoma.
Requires careful histologic distinction from Ewing sarcoma in jaw lesions; leaves open optimal treatment strategies for this rare entity.
Small cell osteosarcoma, a rare histological subtype, has very infrequently been reported in the mandible. We present a case of a 28-year-old female who had classic signs, symptoms, and radiographic features of the lesion. The histology showed sheets of small round cells and osteoid. The absence of the latter would have made it difficult to distinguish from other small round cell tumors of bone, especially Ewing's sarcoma. We have reviewed the clinical and radiographic features, cytologic and histologic characteristics, as well as the immunohistochemistry and molecular genetics of small cell osteosarcoma.
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Uma et al. (2011) conducted a case report in Small cell osteosarcoma of the mandible (n=1). Small cell osteosarcoma was evaluated. A 28-year-old female presented with small cell osteosarcoma of the mandible, characterized by sheets of small round cells and osteoid, distinguishing it from Ewing's sarcoma.
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