Application of the enzyme linked immunosorbent assay to the detection and identification of foot-and-mouth disease viruses

Crowther et al. (1979) studied Foot-and-mouth disease (n=23). Enzyme-linked immunosorbent assay (ELISA) vs. Complement fixation (CF) test was evaluated on Positive typing of FMD virus from original epithelial samples. The double sandwich ELISA successfully typed 19 out of 23 original bovine epithelial samples for foot-and-mouth disease virus, compared to only 8 samples typed by the routine complement fixation test.