The local thermodilution method was adapted for the measurement of renal venous outflow in man. The flow in model experiments varied in the range of 3% from the mean. Clinical measurement on one or successively on both sides was carried out in 35 patients with essential hypertension or proteinuria. In 3 subjects with healthy kidneys the average venous outflow from one kidney was 782 ± 112 ml/min. The average standard deviation of the difference between both kidneys in 7 bilaterally investigated persons was 51 ml/min. The variability of resting flow depended principally on respiration and amounted to 12 to 18%. Comparison of the results of the thermodilution measurement with the PAH-clearance and with the dye dilution technique gave a good correlation and confirmed the usefulness of the thermodilution method for the measurement of the renal blood flow.
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Hornych et al. (2008) studied this question.