Key result
Diabetic ketoacidosis can trigger elevated troponin levels without obstructive coronary artery disease.
Why the study?
Elevated troponin levels occur in patients without ischemic heart disease, including those with diabetic ketoacidosis, creating diagnostic challenges.
Case Report (n=2)
Troponin elevation in diabetic ketoacidosis can occur without obstructive coronary artery disease, requiring careful diagnostic evaluation.
Should not yet change troponin evaluation in DKA; hypothesis-generating case report requiring confirmation in larger cohorts.
Elevated troponin levels have been observed in a wide spectrum of patients who do not have ischemic heart disease, including nonacute coronary syndrome and cardiovascular and noncardiovascular conditions. The cases of two patients with diabetic ketoacidosis who had elevated troponin levels in the absence of coronary artery disease are presented. This clinical scenario can pose a diagnostic dilemma for the physician. The objective of the present report is to highlight the mechanism of troponin elevation in patients with diabetic ketoacidosis, in addition to the clinical and prognostic significance of this finding.
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Ajaydas T. Manikkan (2018) conducted a case report in Diabetic ketoacidosis (n=2). Diabetic ketoacidosis was evaluated on Elevated troponin levels in the absence of coronary artery disease. Elevated troponin levels can occur in patients with diabetic ketoacidosis in the absence of obstructive coronary artery disease, posing a diagnostic dilemma.
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