Key result
Cardiac arrhythmias stem from altered transmembrane potentials disrupting impulse formation or conduction.
Why the study?
Cardiac arrhythmias arise from abnormalities in impulse initiation or conduction due to cellular electrophysiologic alterations often caused by disease.
Design
Review article
Authors
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Outlines cellular arrhythmia mechanisms; leaves open targeted therapies for disease-altered transmembrane potentials.
This review summarizes the cellular electrophysiologic mechanisms underlying cardiac arrhythmias, including abnormalities in impulse initiation and conduction.
Andrew L. Wit (1990) conducted a review in Cardiac arrhythmias. Cardiac arrhythmias result from abnormalities in impulse initiation (automaticity or triggered activity) or conduction (reentrant excitation) due to alterations in transmembrane potentials.
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