Key result
Rheumatic heart disease linked to ~5 mm larger left atrial diameter in AF patients.
Why the study?
Rheumatic heart disease is a common cause of atrial fibrillation in developing countries, and the impact on left atrial and left atrial appendage function requires assessment.
Does left atrial and left atrial appendage function differ between atrial fibrillation patients with and without rheumatic heart disease?
Observational (n=172)
No
Does left atrial and left atrial appendage function differ between atrial fibrillation patients with and without rheumatic heart disease?
In patients with atrial fibrillation, left atrial and left atrial appendage function is more severely impaired in those with rheumatic heart disease compared to those without.
INTRODUCTION: Rheumatic heart disease (RHD) is one of the most typical causes of atrial fibrillation in developing countries like India. The left atrial and left atrial appendage structure and function are deranged in atrial fibrillation and are a major source of thromboembolism. The goal of this study was to assess the left atrial and left atrial appendage function by transesophageal echocardiography in patients with atrial fibrillation and their comparison in patients with or without RHD. METHODS: A total of 172 consecutive patients with atrial fibrillation with or without RHD were subjected to trans-esophageal echocardiography to assess and compare left atrial (LA) and left atrial appendage (LAA) function. Mean LAA emptying velocity was significantly lower in RHD patients than Non-RHD (20.49±3.95 vs. 22.8±5.96 ml/s, p=0.002). CONCLUSION: Rheumatic heart disease is still a common cause of atrial fibrillation in developing countries. LA and LAA function is impaired in atrial fibrillation, more in patients with rheumatic heart disease.
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Jain et al. (2021) conducted an observational in Atrial fibrillation (n=172). Rheumatic heart disease vs. Non-rheumatic heart disease was evaluated on Mean left atrial diameter (p=0.001). Patients with atrial fibrillation and rheumatic heart disease had significantly larger left atrial diameter (52.08 vs 46.67 mm) and lower left atrial ejection fraction compared to those without rheumatic heart disease.
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