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December 10, 2016IJC Heart & VasculatureOpen Access

Patients in SR demonstrated significantly better peak velocity, average velocity, strain, strain rate and deformation than those with AF (p < 0.001).

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Why the study?

Do tissue Doppler imaging and speckle tracking echocardiography parameters of the left atrial appendage differ between patients with atrial fibrillation and sinus rhythm?

Population

80 patients with normal left ventricular ejection fraction, including 40 with sinus rhythm and 40 with…

Comparison

Tissue Doppler imaging and speckle tracking… vs Patients with sinus rhythm (SR).

Design

Cross-sectional

Authors

JKJacek KurzawskiAJAgnieszka Janion−SadowskaMSMarcin Sadowski

Discussion

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Overview

LAA TDI and speckle tracking metrics may aid thrombus detection in persistent AF; hypothesis-generating and requires prospective validation before practice change.

Structured PICO

Do tissue Doppler imaging and speckle tracking echocardiography parameters of the left atrial appendage differ between patients with atrial fibrillation and sinus rhythm?

P
Population
80 patients with normal left ventricular ejection fraction, including 40 with sinus rhythm (SR) and 40 with non-valvular atrial fibrillation (AF) on oral anticoagulants (including patients with LAA thrombus).
I
Intervention
Tissue Doppler imaging (TDI) and speckle tracking echocardiography (STE) of the left atrial appendage (LAA) basal segments (left lateral ridge and baso-medial appendage segment).
C
Comparator
Patients with sinus rhythm (SR).
O
Outcome
Quantitative differences in mechanical function of the LAA basal segments (peak velocity, average velocity, strain, strain rate, and deformation).surrogate

Strain rate in the left lateral ridge measured by Doppler and speckle tracking may serve as a novel parameter correlating with LAA thrombus in patients with atrial fibrillation.

Cite This Study

Kurzawski et al. (2016) studied this question.

synapsesocial.com/papers/6a7396808317ef39e84e68c9https://doi.org/10.1016/j.ijcha.2016.11.003
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluating left atrial appendage function in a subtype of non-valvular atrial fibrillation using transesophageal echocardiography combined with two-dimensional speckle tracking2022 · 6 citations
  2. 2Evaluation of Left Atrial Appendage Functions According to Different Etiologies of Atrial Fibrillation with a Tissue Doppler Imaging Technique by Using Transesophageal Echocardiography2009 · 27 citations
  3. 3Assessment of left atrial appendage function by transesophageal echocardiography. Implications for the development of thrombus.1991 · 484 citations
  4. 4Assessment of left atrial appendage function with transthoracic tissue Doppler echocardiography2009 · 74 citations
  5. 5Relationship Between Left Atrial Appendage Function and Left Atrial Thrombus in Patients With Nonvalvular Chronic Atrial Fibrillation and Atrial Flutter.2002 · 37 citations