Key result
TEE speckle tracking shows diffusely decreased LAA deformability and compliance in persistent versus paroxysmal AF.
Why the study?
LAA dysfunction is closely associated with AF-related stroke, but few studies have evaluated changes in LAA function across different types of AF.
Does transesophageal echocardiography combined with two-dimensional speckle tracking detect differences in left atrial appendage function between paroxysmal and persistent non-valvular atrial fibrillation?
Observational (n=216)
Does transesophageal echocardiography combined with two-dimensional speckle tracking detect differences in left atrial appendage function between paroxysmal and persistent non-valvular atrial fibrillation?
Transesophageal echocardiography with speckle tracking demonstrates that left atrial appendage deformability and compliance are significantly more impaired in persistent compared to paroxysmal non-valvular atrial fibrillation.
Answers are grounded in this paper and cite their sources.
May refine AF subtype phenotyping on TEE speckle tracking; leaves open whether measures predict outcomes or alter management.
Background: The use of transesophageal echocardiography (TEE) is a clinically feasible method for quantitative analysis of left atrial appendage (LAA) function. LAA dysfunction is closely associated with atrial fibrillation (AF)-related stroke. However, there are few studies on the changes in LAA function in patients with different types of AF. This study aimed to observe changes in LAA systolic motion and function in patients with different types of AF by using speckle-tracking echocardiography (STE). Methods: A retrospective study of 216 patients with non-valvular AF was conducted. The LAA was divided into three parts: the basal segment (B), middle segment (M), and top segment (A). Speck -racking technology was used to measure and record the forward strain values of the basal segment (B), middle segment (M), and top segment (A) of the LAA, and the peak positive strain dispersion of the LAA was calculated. The left atrial appendage mechanical dispersion (LAAMD) was defined as the standard deviation (SD) of the peak positive strain at each segment of the R-R interval. Results: 70.85±20.741; P=0.000), and the peak positive strains of the M and A of the LAA were lower than those in the higher LAAMD group. Conclusions: The deformability of the LAA is decreased diffusely in per-AF, especially in the A of the LAA. Compliance with LAA was worse in patients with per-AF than in those with par-AF.
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Wang et al. (2022) conducted an observational in non-valvular atrial fibrillation (n=216). Transesophageal echocardiography combined with two-dimensional speckle tracking vs. Different types of atrial fibrillation (persistent vs paroxysmal) was evaluated on Left atrial appendage systolic motion and function (strain values and mechanical dispersion) (p=0.000). Transesophageal echocardiography with speckle tracking demonstrated that left atrial appendage deformability and compliance are decreased diffusely in persistent AF compared to paroxysmal AF.
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