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January 27, 2009European Journal of EchocardiographyOpen Access

Transthoracic tissue Doppler echocardiography measurement of left atrial appendage contraction velocity correlates strongly with transoesophageal echocardiography (r=0.741, P<0.0001).

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Why the study?

Can transthoracic tissue Doppler echocardiography reliably measure left atrial appendage contraction velocity compared to transesophageal echocardiography for risk stratification in atrial fibrillation?

Population

141 patients referred for transoesophageal echocardiogram (TEE), of which 48 were in atrial fibrillation (AF).

Comparison

Transthoracic tissue Doppler echocardiography to… vs Transoesophageal echocardiogram measurement of…

Design

Cross-sectional

Key result

Transthoracic tissue Doppler echocardiography measurement of left atrial appendage contraction velocity correlates strongly with transoesophageal echocardiography (r=0.741, P<0.0001).

Authors

SUScott UretskyASAjay M. ShahSBSripal Bangalore

Discussion

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Overview

Transthoracic tissue Doppler may substitute for transesophageal echocardiography in atrial fibrillation risk stratification; confirms strong correlation and supports non-invasive validation.

Key Points

  • This research aims to evaluate left atrial appendage contraction velocity as a measure of atrial fibrillation risk.
  • Studied 141 patients referred for transoesophageal echocardiogram; 118 had adequate TTE traces.
  • Measured LAA A(M) velocities using transthoracic echocardiography on the parasternal short-axis and apical two-chamber views.
  • Compared LAA A(M) between patients with atrial fibrillation and sinus rhythm.
  • Patients in AF had lower LAA A(M) on parasternal short-axis (12 +/- 5 vs. 23 +/- 7 cm/s, P < 0.0001).
  • Those with spontaneous echo contrast showed even lower velocities (11 +/- 4 vs. 22 +/- 8 cm/s, P < 0.0001).
  • In patients with AF and LAA A(M) < or =11 cm/s, nearly one-third had LAA thrombus.

Study Design

Type

Observational (n=141)

Structured PICO

Can transthoracic tissue Doppler echocardiography reliably measure left atrial appendage contraction velocity compared to transesophageal echocardiography for risk stratification in atrial fibrillation?

P
Population
141 patients referred for transoesophageal echocardiogram, including 48 with atrial fibrillation, evaluated for left atrial appendage contraction velocity.
E
Exposure
Transthoracic tissue Doppler echocardiography (TTE) to quantify left atrial appendage contraction velocity (LAA A(M)).
C
Comparator
Transoesophageal echocardiogram (TEE) measurement of LAA A(M).
O
Outcome
Correlation between LAA A(M) velocities measured by TEE and TTE.surrogate

Main Result

Effect estimate: r = 0.741

p-value: p=< 0.0001

Cite This Study

Uretsky et al. (2009) conducted an observational in Atrial fibrillation (n=141). Transthoracic tissue Doppler echocardiography (TTE) vs. Transoesophageal echocardiogram (TEE) was evaluated on Correlation between LAA A(M) on TEE and TTE parasternal short-axis (r = 0.741, p=< 0.0001). Transthoracic tissue Doppler echocardiography measurement of left atrial appendage contraction velocity correlates strongly with transoesophageal echocardiography (r=0.741, P<0.0001).

synapsesocial.com/papers/6a6b15c047a1bfb288f3078bhttps://doi.org/10.1093/ejechocard/jen339
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Transthoracic Doppler echocardiography for the assessment of left atrial appendage size and blood flow velocity. A multicentre study2008 · 6 citations
  2. 2Multiplane Transesophageal Echocardiographic Assessment of Left Atrial Appendage2002 · 3 citations
  3. 3Assessment of left atrial appendage function by transthoracic pulsed Doppler echocardiography: Comparing against transesophageal interrogation and predicting echocardiographic risk factors for stroke2017 · 8 citations
  4. 4Evaluation of Left Atrial Appendage Functions According to Different Etiologies of Atrial Fibrillation with a Tissue Doppler Imaging Technique by Using Transesophageal Echocardiography2009 · 27 citations
  5. 5Transthoracic Versus Transesophageal Two‐Dimensional Echo Doppler Determination of Flow Velocity in the Left Atrial Appendage1997 · 18 citations