Key result
Ancient endogenous MMTV sequences are localized in lighter DNA segments (GC ~38%), whereas exogenous and recently acquired sequences are also present in heavier segments (GC ~43%).
Authors
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No immediate clinical implications for oncology; extends models of endogenous retroviral integration by GC content in mammals.
Zerial et al. (1987) studied this question. MMTV proviral sequences was evaluated on Genome distribution of MMTV sequences. Ancient endogenous MMTV sequences are localized in lighter DNA segments (GC ~38%), whereas exogenous and recently acquired sequences are also present in heavier segments (GC ~43%).
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