Key result
Contrast echocardiography resolves inconclusive post-MI scans, changing antithrombotic therapy in ~68% with confirmed LV thrombus.
Why the study?
Conventional echocardiography is often inconclusive for detecting left ventricular thrombus postinfarction, and the additional diagnostic and therapeutic value of contrast echocardiography was investigated.
Does contrast echocardiography improve left ventricular thrombus detection and impact antithrombotic therapy in postinfarction patients compared to conventional echocardiography?
Population
156 postinfarction patients undergoing additional contrast echocardiography
Comparison
Contrast echocardiography vs conventional echocardiography
Design
Cohort study
Authors
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Contrast echo may clarify inconclusive post-MI LV thrombus cases and alter antithrombotic therapy; leaves open prospective outcome trials before routine adoption.
Cohort (n=156)
Does contrast echocardiography improve left ventricular thrombus detection and impact antithrombotic therapy in postinfarction patients compared to conventional echocardiography?
Contrast echocardiography significantly improves the diagnostic accuracy of LV thrombus detection postinfarction, leading to appropriate and clinically meaningful changes in antithrombotic therapy.
Siebelink et al. (2009) conducted a cohort in Post-myocardial infarction (n=156). Contrast echocardiography vs. Conventional echocardiography was evaluated on Left ventricular thrombus detection and change in antithrombotic therapy. Contrast echocardiography resolved all inconclusive conventional echocardiograms for LV thrombus post-infarction, changing antithrombotic therapy in 68% of patients with confirmed thrombus.
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