Key result
Coronary CTA detects mitral valve prolapse with ~96% sensitivity using multi-chamber views.
Why the study?
The diagnostic performance of coronary CT angiography for mitral valve prolapse compared with transthoracic echocardiography was evaluated.
Does coronary CT angiography accurately diagnose mitral valve prolapse compared to transthoracic echocardiography?
Comparison
Coronary CT angiography vs transthoracic echocardiography
Design
Retrospective case-controlled multicenter study with two independent observers
Authors
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May support coronary CTA for MVP detection when TTE is limited; leaves open prospective validation.
Case-Control (n=112)
Yes
Does coronary CT angiography accurately diagnose mitral valve prolapse compared to transthoracic echocardiography?
Coronary CT angiography demonstrates high diagnostic accuracy for mitral valve prolapse when combining three- and two-chamber views, correlating well with transthoracic echocardiography.
Feuchtner et al. (2010) conducted a case-control in Mitral valve prolapse (n=112). Coronary computed tomographic (CT) angiography vs. Transthoracic echocardiography was evaluated on Diagnostic performance of CT for the diagnosis of mitral valve prolapse. Coronary CT angiography using combined three- and two-chamber views accurately diagnosed mitral valve prolapse with 96% sensitivity and 93% specificity.
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