Key result
Successful ATP is associated with greater sinus cycle length shortening during VT vs unsuccessful attempts.
Why the study?
Predictors of antitachycardia pacing (ATP) success in patients with implantable cardioverter defibrillators remain poorly understood.
Does the magnitude of sinus cycle length shortening during ventricular tachycardia predict successful antitachycardia pacing in patients with ICDs?
Population
26 patients with dual-chamber ICDs experiencing 88 VT events
Comparison
Greater sinus cycle length shortening during VT vs lesser shortening
Design
Observational cohort study
Authors
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SCL shortening during VT may predict ATP success in ICD patients; hypothesis-generating and requires prospective validation before guiding therapy.
Observational (n=26)
Does the magnitude of sinus cycle length shortening during ventricular tachycardia predict successful antitachycardia pacing in patients with ICDs?
Absolute Event Rate: 5.8% vs 4.7%
p-value: p=0.007
Sinus cycle length shortening during ventricular tachycardia is a specific predictor of successful antitachycardia pacing, suggesting a potential role in future ICD programming.
MacGregor et al. (2006) conducted an observational in Ventricular tachycardia in patients with implantable cardioverter defibrillators (n=26). Antitachycardia pacing (ATP) success vs. ATP failure was evaluated on Mean sinus cycle length (SCL) shortening (p=0.007). Successful antitachycardia pacing was associated with a significantly greater shortening in sinus cycle length during ventricular tachycardia compared to unsuccessful pacing (5.8% vs 4.7%, P=0.007).
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