Toward the Hypothesis of Cancer Xenogamous Origin of and Circle of Life

The failure of Cancer Crusade (1971Crusade ( -2012) ) revealed extraordinary need to elaborate of more productive paradigm of cancer.The goal of this article is to search and reveal epidemiological, clinical, genetic and immunological evidence of the entirely innovative hypothesis of the xenogamous origin and unique parasite subsistence of human cancer.The investigation was grounded on a multidisciplinary integrative reassessment and reinterpretation of both the current and newest data on cancer from the viewpoint of recent achievements in epidemiology, immunology, molecular interspecies ecology and the theory of biological evolution.It is shown that the multiplicity of traits that belong to cancer are performed by a causative agent of the disease, an unique biological entity that evolved to invade the human body and to subsist in it at the expense of the materials, energy and functions of the invaded organism over consecutive stages of cancer subsistence, beginning from the invasion of victim's with cancerous gamete and finishing with the sexual transmission of cancer among people.The results achieved and the conclusions reached provide a new framework and new landmarks for understanding cancer epidemics and encourage new proposals for cancer prevention and therapy by means of newly oriented genetic, immunological and molecular ecological approaches.