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May 1, 1971Annals of Internal Medicine

Diagnosis of Hypertrophic Subaortic Stenosis with a Doppler Velocity Flow Detector

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Key result

Transcutaneous Doppler detects abnormal carotid flow in 100% of HSS patients vs. other heart diseases.

  • n=106

Why the study?

The clinical evaluation of hypertrophic subaortic stenosis lacks a validated noninvasive method to detect its distinct flow pattern in the carotid artery.

Does a transcutaneous Doppler velocity probe accurately identify hypertrophic subaortic stenosis by detecting abnormal phasic carotid artery flow?

Population

12 patients with hypertrophic subaortic stenosis and 94 patients with other cardiovascular disease

Comparison

Phasic carotid artery flow in hypertrophic subaortic stenosis vs other cardiovascular disease

Design

Cross-sectional study using transcutaneous Doppler velocity probe

Authors

CJClaude R. JoynerL3Harris (United Kingdom)

Discussion

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Implication

Carotid Doppler may aid noninvasive detection of hypertrophic subaortic stenosis; leaves open prospective validation of diagnostic utility.

Study Design

Type

Cross-Sectional (n=106)

Structured PICO

Does a transcutaneous Doppler velocity probe accurately identify hypertrophic subaortic stenosis by detecting abnormal phasic carotid artery flow?

P
Population
106 patients, comprising 12 with hypertrophic subaortic stenosis and 94 with other cardiovascular diseases.
E
Exposure
Transcutaneous Doppler velocity probe recording of phasic carotid artery flow
C
Comparator
Patients with other cardiovascular disease (n=94)
O
Outcome
Presence of abnormal Doppler flow pattern (sharp wave of rapid early systolic flow, abrupt decrease in midsystole, slower late systolic flow)surrogate

Main Result

Absolute Event Rate: 100% vs 0%

Transcutaneous Doppler velocity recording of phasic carotid flow is a valid clinical tool for evaluating hypertrophic subaortic stenosis, identifying abnormal flow patterns even when characteristic pulse contours are absent.

Cite This Study

Claude R. Joyner (1971) conducted a cross-sectional in Hypertrophic subaortic stenosis (n=106). Transcutaneous Doppler velocity probe vs. Patients with other cardiovascular disease was evaluated on Abnormal abrupt decrease in midsystolic flow. A transcutaneous Doppler velocity probe detected an abnormal carotid flow profile in 100% of patients with hypertrophic subaortic stenosis, compared to 0% of 94 patients with other cardiac diseases.

synapsesocial.com/papers/6ab4a7a8c00cd19ff64d3cffhttps://doi.org/10.7326/0003-4819-74-5-692

Topics

Hypertrophic cardiomyopathy
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A Hemodynamic Technic for the Detection of Hypertrophic Subaortic Stenosis1961 · 244 citations
  2. 2Idiopathic Hypertrophic Subaortic Stenosis: III. Intraoperative Studies of the Mechanism of Obstruction and Its Hemodynamic Consequences1964 · 86 citations
  3. 3The Clinical, Hemodynamic, and Pathologic Diagnosis of Muscular Subvalvular Aortic Stenosis1961 · 151 citations
  4. 4HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY1964 · 194 citations
  5. 5The Effects of Mitral Regurgitation on the Pattern of Instantaneous Aortic Blood Flow Clinical and Experimental Observations1967 · 23 citations