Key result
Arterial blood gas manipulations (hypoxia, hypercapnia, hypocapnia) disrupted task-related neurovascular coupling and modulated spontaneous alpha oscillatory activity.
Why the study?
Do alterations in arterial blood gases affect neural responses and cerebral blood flow during rest and sustained attention in human participants?
Population
Human participants
Comparison
Alterations in arterial blood gases vs Normoxia
Design
Other
Authors
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Blood gas alterations may disrupt task-related neurovascular coupling and modulate attention-related EEG; hypothesis-generating for cognitive impairment mechanisms in hypoxia.
Do alterations in arterial blood gases affect neural responses and cerebral blood flow during rest and sustained attention in human participants?
Transient arterial blood gas changes, such as hypocapnia and hypercapnia, can modulate multiple stages of cognitive information processing and disrupt neurovascular coupling.
Bullock et al. (2021) studied this question. Arterial blood gas manipulations (hypoxia, hypercapnia, hypocapnia) vs. Normoxia was evaluated on Spontaneous and task-specific fluctuations in neural activity and cerebral blood flow. Arterial blood gas manipulations (hypoxia, hypercapnia, hypocapnia) disrupted task-related neurovascular coupling and modulated spontaneous alpha oscillatory activity.
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