Respiratory Stability Time Transition in Acute Decompensated Heart Failure with Reduced Left Ventricular Ejection Fraction

A novel telemonitoring system utilizing contactless sensor technologies combined with automated overnight respiratory stability time (RST) analysis has emerged as a sensitive and specific indicator of worsening heart failure (HF), enabling early clinical exacerbation identification. However, the correlation between the RST trajectory and other clinical parameters, as well as targeted therapeutic strategies for improving RST in patients experiencing acute decompensated HF, remains unclear. Herein, we present two cases of hospitalized patients with HF and reduced left ventricular ejection fraction, which were successfully managed through clinical interventions monitored by integrated RST parameters. A significant recovery in RST was observed following the improvement of congestion and hypoperfusion. Further research is warranted to validate the clinical efficacy of RST-directed therapeutic approaches in the management of HF.