Evaluation of lipid nanoparticle adjuvants with different PEG lipid ratios and phospholipid modifications in non-human primates

T cell responses across LNP groups, although not all comparisons reached statistical significance, likely due to the limited sample size. While this study was exploratory, the findings differed from those previously obtained with these LNPs in mice, confirming the importance of assessing LNP formulations in non-human primates prior to clinical evaluation.