Key result
Older age linked to increased morning blood pressure surge and systolic variability in hypertension.
Why the study?
Blood pressure variability and morning systolic blood pressure surge and their associated factors in elderly hypertensive Chinese patients were not well characterized.
Observational (n=701)
No
p-value: p=<.05
In Chinese hypertensive patients, elderly age is associated with increased blood pressure variability and morning blood pressure surge, which are also linked to BMI and smoking.
Alerts clinicians to heightened BP variability in elderly hypertensives; leaves open whether targeting morning surge improves outcomes.
This retrospective study aimed to investigate blood pressure variability (BPV), morning systolic blood pressure surge (MBPS), and the associated factors in 513 elderly (65 years and older) and 188 younger (younger than 65 years) hypertensive Chinese patients who had ambulatory blood pressure monitoring (ABPM) at our hospital from January 1, 2002, to December 31, 2010. The MBPS was lower in the younger patients compared with the elderly patients, and it was highest in the 75 years and older and younger than 80 group (29.0±13.4 mm Hg). Compared with other groups, the 80 years and older group had a significant increase in BPV (P<.05). Multiple linear regression analysis showed that body mass index (BMI; P<.01), up to 50 years of smoking (P≤.03), and circadian blood pressure variation (P<.01) were factors associated with MPBS. In summary, systolic BPV and MBPS were increased in elderly Chinese hypertensive patients, and the MBPS was associated with BMI, years of smoking, and circadian blood pressure variation.
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Qin et al. (2014) conducted an observational in Hypertension (n=701). Older age (≥65 years) vs. Younger age (<65 years) was evaluated on Morning systolic blood pressure surge (MBPS) and blood pressure variability (BPV) (p=<.05). Elderly hypertensive patients (≥65 years) had increased systolic blood pressure variability (P<.05 for ≥80 years) and morning blood pressure surge compared to younger patients.
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