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The growth of a threonine-sensitive and -requiring strain of Brevibacterium flavum, QL-5, depended on the threonine concentration in a minimal medium, but it was much slower than that of a simple threonine-requiring mutant, T-36, at a low concentration of threonine.This slow growth of the former was stimulated by the addition of isoleucine plus serine or NaCl.
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Shiio et al. (1973) studied this question.
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