Key result
Higher APACHE scores link to increased postoperative complications and earlier mortality in surgical patients.
Why the study?
Variables in ACS-NSQIP data may be effective mortality predictors and could assist in identifying potential complications earlier in critically ill surgical patients.
Cohort (n=340)
No
APACHE score predictions are consistent with ACS-NSQIP-recorded postoperative outcomes in critically ill surgical patients.
APACHE may aid risk stratification in surgical ICU patients; extends NSQIP consistency but leaves open prospective validation.
BACKGROUND: Similarity between the ICU patient data acquired by the APACHE system and the patient outcomes data acquired by the American College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP) suggests that variables in NSQIP data could be effective mortality predictors. We theorized that identifying ACS-NSQIP preoperative data points predictive of patient outcomes would assist in identifying potential complications earlier. STUDY DESIGN: Between 2006 and 2008 at the University of Maryland Medical Center, we identified 340 surgical ICU patients included in both databases as our study cohort. Median APACHE score calculation permitted division of study subjects into quartiles from which to examine length of stay, mortality variables, and ACS-NSQIP-recorded postoperative occurrences and preoperative risk factors. Outcomes were compared using each database's percentage of patients who had died. RESULTS: Mortality was positively correlated with APACHE score increases. Initially, the average ICU length of stay increased, then declined. Most common postoperative occurrences were ventilator dependence >48 hours, pneumonia, unplanned intubation, sepsis, and septic shock. It was also noted that preoperative variables, such as American Society of Anesthesiologists classification and serum albumin levels, had an association with a poorer prognosis. CONCLUSIONS: APACHE score predictions are consistent with ACS-NSQIP-recorded postoperative outcomes. Higher APACHE scores correlated with increased incidence of postoperative outcomes and were associated with earlier mortality in the most extremely ill. Poorer states of health before surgery also correlated with poor outcomes postoperatively.
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Turner et al. (2011) conducted a cohort in Critically ill surgical patients (n=340). APACHE score and ACS-NSQIP preoperative variables was evaluated on Mortality and postoperative occurrences. Higher APACHE scores and poorer preoperative health states correlated with increased postoperative complications and earlier mortality in critically ill surgical patients.
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