Key result
Centrifugal pumps are linked to fewer perioperative neurological complications vs. roller pumps in cardiac surgery.
Why the study?
The influence of the type of pump used for cardiopulmonary bypass (roller vs centrifugal) on neurological outcomes in adult cardiac surgery patients was unclear.
Does the use of a centrifugal pump compared to a roller pump reduce perioperative neurological complications in adult patients undergoing cardiac surgery?
Cohort (n=3,438)
No
Does the use of a centrifugal pump compared to a roller pump reduce perioperative neurological complications in adult patients undergoing cardiac surgery?
The use of a centrifugal pump during cardiopulmonary bypass in adult cardiac surgery may significantly reduce the risk of severe perioperative neurological complications compared to a roller pump.
Answers are grounded in this paper and cite their sources.
Centrifugal pump use was associated with lower adjusted risk of permanent deficit and coma; leaves open confirmation in contemporary randomized trials.
This study was performed to assess if the kind of pump used for CPB (roller vs. centrifugal) can influence neurological outcomes of adult cardiac surgery patients. Between 1994 and 1998, 3438 patients underwent coronary and/or valve surgery at our hospital; of these, 1805 (52.5%) underwent surgery with the use of a centrifugal pump, and 1633 (47.5%) were operated with a roller pump. The effect of the type of the pump and of common preoperative and intraoperative risk factors for five different neurological outcomes (permanent neurological deficit, coma, delirium, transient neurological deficit, overall neurological complications) were assessed with univariate and multivariate analyses in the whole patients population, in patients > or = 75 years old and in patients with histories of previous neurological events. Centrifugal pump use was the only protective factor for perioperative permanent neurological deficit in multivariable models developed for the whole patient population and for patients > or = 75 years old. In addition, it resulted as the only protective factor for perioperative coma occurrence in multivariable models developed for patients > or = 75 years old, and for patients with histories of previous neurological events. The use of the centrifugal pump provided a risk reduction for the considered events ranging from 23 to 84%. Centrifugal pump use can be helpful in reducing the occurrence of some of the most feared neurological complications of adult cardiac surgery patients.
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Alamanni et al. (2001) conducted a cohort in Adult cardiac surgery (n=3,438). Centrifugal pump vs. Roller pump was evaluated on Perioperative neurological outcomes (permanent neurological deficit, coma, delirium, transient neurological deficit, overall neurological complications) (Risk reduction 23-84%). Centrifugal pump use during adult cardiac surgery was associated with a 23% to 84% risk reduction for perioperative neurological complications compared to roller pumps.
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