Key result
Centrifugal pumps are linked to ~42% lower permanent neurological deficits vs. roller pumps, without affecting mortality.
Why the study?
The impact of cardiopulmonary bypass pump type (roller vs centrifugal) on mortality and neurological outcomes in adult cardiac surgery patients was unclear.
Does the use of a centrifugal pump compared to a roller pump for cardiopulmonary bypass reduce mortality or neurological complications in adult cardiac surgery patients?
Population
4000 consecutive adult patients undergoing coronary and/or valve surgery
Comparison
Centrifugal pump vs roller pump for cardiopulmonary bypass
Design
Observational cohort study with univariate and multivariate analyses
Follow-up
In-hospital
Authors
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Centrifugal pump use was associated with fewer neurological complications; leaves open whether randomized trials will confirm benefit or alter pump selection.
Cohort (n=4,000)
No
Does the use of a centrifugal pump compared to a roller pump for cardiopulmonary bypass reduce mortality or neurological complications in adult cardiac surgery patients?
Absolute Event Rate: 2.3% vs 2.1%
p-value: p=0.86
The use of centrifugal pumps during adult cardiac surgery is associated with a significant reduction in major neurological complications compared to roller pumps, though in-hospital mortality remains unaffected.
Alessandro Parolari (2000) conducted a cohort in Adult cardiac surgery (coronary and/or valve surgery) (n=4,000). Centrifugal pump vs. Roller pump was evaluated on In-hospital mortality (p=0.86). Centrifugal pump use during cardiac surgery was associated with lower rates of permanent neurological deficit (1.5% vs 2.6%; P=0.020) compared to roller pumps, with no difference in mortality.