P792Smoking is the dominating modifiable risk factor in younger patients with STEMI

Introduction: Smoking is an important modifiable risk factor for myocardial infarction. It is unclear whether smoking habits at the time of an incident STEMI differ across age groups and sex. Methods: We included patients with incident STEMI registered in The Western Denmark Heart Registry from 2005 to 2015 (n=9,914). Patients were divided into four age groups (30–49, 50–59, 60–69, and ≥70 years) with the latter serving as reference. Results: Smoking was the most prevalent modifiable risk factor in 30–49 year old patients (74% vs hypertension 15%, hyperlipidaemia 10%, and diabetes 7%). The smoking prevalence decreased with increasing age, while treatment for hypertension, hyperlipidaemia, and diabetes increased with increasing age. Smoking was five times (odds ratio (OR): 5.15; 95% confidence interval (CI) 4.37; 6.07) more prevalent among 30–49 years old patients with STEMI than the reference group. Differences according to sex were significant as the OR for current smoking in women was 9.88 (95% CI 6.94; 14.08) compared to OR 3.78 (95% CI 3.12; 4.58) in men.