Key result
Younger age (30-49 years) in patients with STEMI was associated with a significantly higher prevalence of smoking compared to patients ≥70 years (74% prevalence; OR 5.15; 95% CI 4.37-6.07).
Why the study?
Does the prevalence of smoking at the time of incident STEMI differ across age groups and sex?
Observational (n=9,914)
Does the prevalence of smoking at the time of incident STEMI differ across age groups and sex?
Smoking remains the dominant modifiable risk factor in younger patients (30-49 years) presenting with STEMI, with a particularly strong association observed in young women.
Smoking predominates in young STEMI patients; hypothesis-generating for age-specific prevention, needs prospective validation.
AIMS: Smoking is an important modifiable risk factor for myocardial infarction. It is unclear whether smoking habits at the time of an incident ST-segment elevation myocardial infarction (STEMI) differ across age groups and sex. METHODS AND Patients were divided into four age groups (30-49, 50-59, 60-69 and ⩾70 years) with the latter serving as reference. Smoking was the most prevalent modifiable risk factor in 30-49-year-old patients (74% vs. hypertension 15%, hyperlipidaemia 10% and diabetes 7%). The smoking prevalence decreased with increasing age, while treatment for hypertension, hyperlipidaemia and diabetes increased with increasing age. Smoking was five times (odds ratio (OR) 5.15; 95% confidence interval (CI) 4.37-6.07) more prevalent among 30-49-year-old patients with STEMI than the reference group. Differences according to sex were significant as the OR for current smoking in women was 9.88 (95% CI 6.94-14.08) compared to OR 3.78 (95% CI 3.12-4.58) in men. CONCLUSIONS: Despite public information campaigns and general warnings, smoking remains the most prevalent modifiable risk factor in younger patients with STEMI.
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Gleerup et al. (2018) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=9,914). Younger age (30-49 years) vs. Age ≥70 years was evaluated on Smoking prevalence (OR 5.15, 95% CI 4.37-6.07). Younger age (30-49 years) in patients with STEMI was associated with a significantly higher prevalence of smoking compared to patients ≥70 years (74% prevalence; OR 5.15; 95% CI 4.37-6.07).
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