September 1, 2026European Heart Journal Acute Cardiovascular Care
PRAGUE-26 in perspective: convincing early stabilization, but durable benefit remains unproven
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“In contrast to interventions for myocardial infarction or stroke, there have been very few advances in the treatment of pulmonary embolism over the last 20 years. This has led to a considerable unmet clinical need that we can't ignore.”
“We primarily tracked the patient's clinical condition, not just changes in imaging or lab results.”
JKJosef KroupaCardiologist, Charles University and University Hospital Kralovske Vinohrady, Prague
“no study of this scale had previously compared the new approach with standard treatment based on real clinical outcomes for patients.”
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Grand et al. (2026) studied this question.