Key result
Influenza virus defective interfering particles are common during natural infection and may play an important role in influencing viral persistence and pathogenicity.
Design
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DIPs may shape influenza outcomes clinically; leaves open their therapeutic targeting pending prospective validation.
This paper discusses the history and ongoing mysteries surrounding the production of defective interfering particles during influenza virus infection.
Alnaji et al. (2020) conducted a review in Influenza virus infection. Defective interfering particles (DIPs) was evaluated. Influenza virus defective interfering particles are common during natural infection and may play an important role in influencing viral persistence and pathogenicity.
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