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October 1, 1990Muscle & Nerve

Electrophysiological spectrum of inclusion body myositis

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Key result

Electromyography in inclusion body myositis demonstrated a heterogeneous profile, with a mixed pattern of large and small motor unit potentials seen in 36.7% of patients.

Why the study?

What are the electrophysiological features of inclusion body myositis?

Population

30 patients with inclusion body myositis (IBM)

Design

Case_series

Authors

JJJuan L. JoyUniversity of Alabama at BirminghamSOShin J. OhMokpo National UniversityABAli İhsan BaysalTokat Gaziosmanpaşa Üniversitesi

Discussion

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Implication

Mixed EMG motor unit potentials may support inclusion body myositis suspicion in select cases; leaves open prospective validation of diagnostic criteria.

Study Design

Type

Observational (n=30)

Structured PICO

What are the electrophysiological features of inclusion body myositis?

P
Population
30 patients with inclusion body myositis undergoing comprehensive electromyography and nerve conduction studies.
E
Exposure
Comprehensive electromyography (EMG) and nerve conduction studies (NCS), with single fiber electromyography (SFEMG) in 12 patients
O
Outcome
Electrophysiological features and patterns on EMG and NCSsurrogate

Inclusion body myositis demonstrates a heterogeneous EMG profile, with a mixed pattern of large and small MUPs being highly suggestive but present in only about one third of cases.

Cite This Study

Joy et al. (1990) conducted an observational in Inclusion body myositis (n=30). Electromyography and nerve conduction studies was evaluated on Electrophysiological features. Electromyography in inclusion body myositis demonstrated a heterogeneous profile, with a mixed pattern of large and small motor unit potentials seen in 36.7% of patients.

synapsesocial.com/papers/6ab5ceba11ffef926e20b12chttps://doi.org/10.1002/mus.880131010
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiac Features of an Unusual X-Linked Humeroperoneal Neuromuscular Disease1975 · 97 citations
  2. 2Inclusion‐body myositis: Clinicopathological studies and isolation of an adenovirus type 2 from muscle biopsy specimen1982 · 63 citations
  3. 3Inclusion Body Myositis Associated with Systemic Sarcoidosis1986 · 39 citations
  4. 4Clinical Electromyography: Nerve Conduction Studies1984 · 453 citations
  5. 5Phytanic acid storage disease1983 · 39 citations