Key result
Prednisolone improves LVEF to 31% in eosinophilic myocarditis associated with Kimura disease.
Why the study?
Eosinophilic myocarditis complicated by Kimura's disease and erythroderma is a rare clinical presentation requiring detailed case description.
Case Report (n=1)
No
Steroid therapy was effective in improving left ventricular function and eosinophilia in a rare case of eosinophilic myocarditis complicated by Kimura's disease and erythroderma.
May alert clinicians to eosinophilic myocarditis in Kimura's disease or erythroderma; leaves open a potential syndromic link.
This report describes a patient with eosinophilic myocarditis complicated by Kimura's disease (eosinophilic hyperplastic lymphogranuloma) and erythroderma. A 50-year-old man presented with a complaint of precordial pain. However, the only abnormal finding on examinatioin was eosinophilia (1617 eosinophils/microl). Three years later, the patient developed chronic eczema, and was diagnosed with erythroderma posteczematosa. One year later, a tumor was detected in the right auricule, and a diagnosis of Kimura's disease was made, based on the biopsy findings. The patient developed progressive dyspnea 6 months later and was found to have cardiomegaly and a depressed left ventricular ejection fraction (17%). A diagnosis of eosinophilic myocarditis was made based on the results of a right ventricular endomyocardial biopsy. The eosinophilic myocarditis and erythrodrema were treated with steroids with improvement of both the eosinophilia and left ventricular function.
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Nakagawa et al. (1999) conducted a case report in Eosinophilic myocarditis complicated by Kimura's disease and erythroderma (n=1). Prednisolone was evaluated on Left ventricular ejection fraction and eosinophil count. Steroid therapy with prednisolone effectively reduced peripheral eosinophils and improved left ventricular ejection fraction from 17% to 31% in a patient with eosinophilic myocarditis and Kimura's disease.
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