A General Way, From L-Ascorbic And D-Isoascorbic Acids, To Homochiral α-Hydroxy, α,β-Dihydroxy And α,β-Epoxy-Aldehydes, Useful Building Blocks For The Synthesis Of Linear Oxygenated Fatty Acids Metabolites

Enantiomerically pure α-hydroxy, α,β-dihydroxy and α,β-epoxyaldehydes, useful building blocks for the synthesis of acyclic oxygenated fatty acids metabolites, were synthetized via epoxybutanediol acetonide starting from the commercially available L-ascorbic and D-isoascorbic acids.