Answers are grounded in this paper and cite their sources.
The effect of pretreatment with topical prostaglandin E2, prednisolone and sulphasalazine in experimental colitis has been examined in the rat colon. Only prostaglandin E2 treatment significantly reduced mucosal ulceration. Long-term exposure of the rat colon to topical ethanol produced some of the histological changes seen in human colitis.
No takes yet. Share an insight, caveat, or question.
Psaila et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: