Key result
Obesity in T2D is linked to larger thyroid volumes, tracking with adiposity and insulin resistance.
Why the study?
Increased circulating insulin levels correlated with insulin resistance impact thyroid tissue, but the relationship between thyroid volume, function, and echogenicity in obese type 2 diabetics was not well characterized.
Case-Control (n=60)
No
Obese patients with type 2 diabetes exhibit larger thyroid volumes that correlate significantly with markers of adiposity and insulin resistance.
Answers are grounded in this paper and cite their sources.
Larger thyroid volumes in obese T2D warrant no practice change; case-control data leave causal and screening implications open.
Background an increased levels of circulating insulin hormone is correlated with insulin resistance and impacted on thyroid tissue resulting in larger thyroid volume. Aim and objectives: To assess the thyroid volume and thyroid function tests and ultrasonography echogenicity in obese diabetics with type 2 diabetes. Subjects and methods: This research included 60 studied cases, Group (A): including 40 patients: Obese type 2 DM Group (B): including 20 normal persons as a control group They were collected from the outpatient clinics of Al-Hussein University Hospital between January and July 2022. Results: Our result show that There is highly significance difference between group A (obese diabetic patients) and group B (the control group) we also discovered a significant relationship among thyroid volume and Body Mass Index in relation to thyroid volume and thyroid ultrasound echogenicity., waist circumference, glycated HGB and HOMA-IR comparing to group B (the control group). Conclusion: Our findings imply that type II diabetes mellitus patients with obesity have larger thyroid volumes with a highly statistically correlation with BMI, WC, HbA1C, and HOMA-IR.
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Emara et al. (2023) conducted a case-control in Obese type 2 diabetes mellitus (n=60). Obese type 2 diabetes mellitus vs. Normal persons was evaluated on Thyroid volume and ultrasound echogenicity. Obese patients with type 2 diabetes mellitus had significantly larger thyroid volumes that correlated with BMI, waist circumference, HbA1c, and HOMA-IR compared to normal controls.
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