Mirtazapine for Anorexia Nervosa with Depression

OBJECTIVE: To report the use of Mirtazapine in the treatment of anorexia nervosa with depression primarily regarding its propensity for weight gain. METHOD: We present an outpatient case report of anorexia nervosa with depression. The patient's subsequent progress was recorded. RESULTS: The patient gained 2.5 kg within 3 months to eventually attain a body mass index of 15 after 5 months. Her depression achieved full remission at 6 weeks of treatment. CONCLUSIONS: Mirtazapine is the choice medication in this case. However, treating depression requires caution, given these patients' physical vulnerability. Controlled trials of Mirtazapine for anorexia nervosa are needed.