Key result
Accurate differential diagnosis of angina prevents life-threatening underdiagnosis and iatrogenic overdiagnosis.
Why the study?
Differential diagnosis of angina pectoris is challenging due to overlapping manifestations with esophageal, neurotic, and neurological disorders, leading to risks of under- or overdiagnosis.
Accurate differential diagnosis of chest pain is critical to avoid life-threatening underdiagnosis of angina and harmful overdiagnosis leading to unjustified hospitalization.
Answers are grounded in this paper and cite their sources.
Demands precise angina differentiation in chest pain; hypothesis-generating without prospective validation.
The article examines the differential diagnostic aspects of chest pain syndrome from a cardiological point of view. Pathologies that may be similar in their manifestations to the angina pectoris include esophageal diseases, neurotic disorders and some neurological syndromes. Underdiagnosis of angina pectoris a direct threat to the patient's life. Overdiagnosis of angina leads to unjustified hospitalization, increases the risk of iatrogenism and exacerbates the course of an unrecognized extracardial disease. In practice, the greatest diagnostic difficulties arise when the paroxysmal chest pain is not associated with physical exertion, is absent during a medical examination, and the "pain history" itself is short – several hours or days.
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А. Г. Еремеев (2025) conducted a review in Chest pain syndrome and angina pectoris. Accurate differential diagnosis of angina pectoris from esophageal, neurotic, and neurological syndromes is critical to prevent life-threatening underdiagnosis and iatrogenic overdiagnosis.
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