Key result
Post-bypass balloon angioplasty yields higher angiographic success in grafts than native vessels at ~90%.
Why the study?
The feasibility, safety, and effectiveness of percutaneous transluminal coronary angioplasty in patients with prior coronary artery bypass grafting and recurrent angina were not well established.
Does balloon angioplasty improve angiographic stenosis in patients with prior coronary artery bypass grafting and recurrent angina?
Observational (n=134)
Does balloon angioplasty improve angiographic stenosis in patients with prior coronary artery bypass grafting and recurrent angina?
Absolute Event Rate: 90% vs 74%
Percutaneous transluminal coronary angioplasty is a feasible and effective therapy with a low complication risk for symptomatic patients with prior bypass surgery.
PTCA after CABG achieved high procedural success at 3% major complication risk; leaves open its comparative efficacy versus modern PCI or redo surgery in randomized data.
Between 1982 and 1990, in 134 patients with prior coronary artery bypass grafting and recurrent angina, repeat coronary angiography and balloon angioplasty of stenoses in grafts or native arteries were attempted. Mean age of grafts was 45.6 months, range three days to twelve years. At the time of angioplasty, 6 patients had one-vessel-disease, 33 had two-vessel-disease, and 95 had three-vessel-disease. A total of 182 lesions were dilated: 55 venous grafts, 3 internal mammary artery grafts, and 124 native vessels. Forty-nine of 55 (89%) venous grafts could be successfully dilated, and in 3 internal mammary artery grafts, a stenosis reduction greater than 50% was achieved. In 65 of 88 (74%) grafted native arteries, dilation success was achieved. Twenty-seven of 36 (75%) patients with prior bypass surgery to other arteries had successful angioplasty of nongrafted native arteries. Three patients underwent emergency bypass surgery after dissection and acute occlusion: one of them died in cardiogenic shock secondary to acute myocardial infarction. The angiographic success rate in grafts was slightly higher than in native arteries (90% vs 74%). These data indicate that percutaneous transluminal coronary angioplasty in patients after bypass surgery is possible at a low risk (3%) and constitutes an effective therapy in symptomatic patients.
No takes yet. Share an insight, caveat, or question.
Unterberg et al. (1992) conducted an observational in prior coronary artery bypass grafting and recurrent angina (n=134). Balloon angioplasty in grafts vs. Balloon angioplasty in native arteries was evaluated on angiographic success rate. Balloon angioplasty in patients with prior bypass surgery achieved an angiographic success rate of 90% in grafts compared to 74% in native arteries, with a low overall risk of 3%.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: