Key result
Lower FEV1 and FVC are linked to worsening NYHA functional class in mitral stenosis.
Why the study?
Pulmonary function derangements in mitral stenosis and their correlation with clinical and hemodynamic parameters require evaluation for preoperative assessment.
Population
25 patients with isolated or predominant mitral stenosis selected for mitral valve surgery
Comparison
Pulmonary function test derangements correlated with clinical profile, mitral stenosis severity, and pulmonary hypertension severity
Design
Cross-sectional study
Authors
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May aid symptom assessment in mitral stenosis; hypothesis-generating for PFTs as congestion markers, not stenosis severity.
Cross-Sectional (n=25)
Pulmonary function test derangements in mitral stenosis correlate with NYHA functional class and pulmonary venous congestion, but not directly with echocardiographic severity of stenosis or pulmonary hypertension.
Parvathy et al. (2014) conducted a cross-sectional in isolated or predominant mitral stenosis (n=25). Mitral stenosis severity and clinical profile was evaluated on Correlation of pulmonary function test derangements with clinical profile and severity of mitral stenosis. In patients with mitral stenosis, spirometric parameters such as FVC (r=-0.4, p=0.04) and FEV1 (r=-0.5, p=0.01) correlated significantly with increasing NYHA functional class.
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