Key result
125I-fibrinogen scanning accurately identifies thrombus depth in lower limb DVT confirmed by phlebography.
Why the study?
A noninvasive method to determine the depth of thrombi in the lower limb was needed as an alternative to phlebography for diagnosing postoperative thrombosis.
Does injection of fibrinogen labelled with iodine 125 accurately determine the depth of lower limb thrombi compared to phlebography?
Comparison
125I-fibrinogen method vs phlebography and clinical examination
Design
Observational study
Authors
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May support 125I-fibrinogen for lower-limb thrombus localization; leaves open validation versus phlebography before clinical adoption.
Observational (n=9)
Does injection of fibrinogen labelled with iodine 125 accurately determine the depth of lower limb thrombi compared to phlebography?
The 125I-fibrinogen method accurately determines the depth of lower limb thrombi, offering a potential alternative to phlebography for diagnosing postoperative thrombosis.
Jacobsson et al. (1980) conducted an observational in Lower limb thrombi (n=9). 125I-fibrinogen method vs. Phlebography and clinical examination was evaluated on Localization and depth of thrombi. The 125I-fibrinogen method successfully determined the depth of 12 lower limb thrombi in 9 patients, with localization confirmed in all cases by phlebography and clinical examination.
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