Key result
Combined diabetes and hypertension increases risk and mortality from stroke, nephropathy, and peripheral vascular disease.
Why the study?
The coexistence of diabetes mellitus and hypertension increases risk and mortality from vascular and renal complications, but the underlying physiological mechanisms are poorly understood.
This review highlights the increased cardiovascular and renal risks associated with coexisting diabetes and hypertension, emphasizing the need for targeted evaluation and treatment.
Answers are grounded in this paper and cite their sources.
Emphasizes heightened vascular risks in comorbid diabetes and hypertension; leaves open mechanistic insights for targeted therapies.
We note that diabetes mellitus and hypertension coexist at a greater rate than would be indicated by chance. The combination of these two chronic disorders increases the risk of and mortality from such conditions as peripheral vascular disease, stroke, and nephropathy. Despite the importance of high blood pressure in diabetes, the underlying physiological mechanisms in this combined condition are poorly understood. This review explores the epidemiology, cardiovascular risks, pathophysiology and evaluation of this condition as well as outlining a general approach to treatment in the hypertensive diabetic.
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Sowers et al. (1990) conducted a review in Hypertension and Diabetes Mellitus. Hypertension in diabetic patients was evaluated. The combination of diabetes mellitus and hypertension increases the risk of and mortality from peripheral vascular disease, stroke, and nephropathy.
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